I’ve just presented the paper “Adapting The Secretary Hiring Problem for Optimal Hot-Cold Tier Placement under Top-K Workloads” at DBDM, CCGrid here in Larnaca, Cyprus.
The paper examines analytic solutions to optimization problems related to tiered/hierarchical storage under Top-K queries with HASTE, and its relation to the classic discrete optimization ‘Secretary Hiring Problem’.
PhD students Håkan Wieslander, Phil Harrison and Ankit Gupta visited Astra Zeneca, hosted by Johan Karlsson and Alan Sabirsh. They had three intense days in the lab getting the high-throughput microscope to talk to the HASTE code. It’s not every day a computer scientist gets to dress up in a lab coat!
We welcome Ankit Gupta as new PhD Student in the Wählby Lab at the Department of Information Technology, Uppsala University.
Ankit obtained his Bachelor’s in Electrical Engineering at Indian Institute of Technology Indore in 2014. Then, he completed his Masters in Medical Imaging and Informatics at Indian Institute of Technology Kharagpur in 2017. Before moving to Uppsala, he was employed as Research Engineer at the University of Bern where he worked on developing a video-based instrument tracking system in stereoscopic laparoscopic surgery.
About the PhD project within HASTE:
Within the project, he will work on developing measurements for the early detection of informative data from large-scale spatial and temporal experiments.
Everyone presented their latest work, and discussed the latest image datasets from AstraZeneca and Vironova. During the software workshop session, we discussed linking the HASTE cloud pipeline to the Vironova MiniTEM.
Thanks to: Carolina Wählby, Ola Spjuth, Andreas Hellander, Ida-Maria Sintorn, Alan Sabirsh, Ernst Ahlberg Helgee, Johan Karlsson, Håkan Wieslander, Philip Harrison, Salman Toor, Ben Blamey, Håkan Öhrn, Markus M. Hilscher, Niharika Gauraha, Magnus Larsson, Oliver Stein, Andy Ishak
HASTE has been featured in ‘Framtidens Forskning’: “As more and more instruments are generating more and more data, we need new methods to not completely drown in data volumes. Our tools make it possible to know in advance where to focus the analysis, which greatly reduces time-consuming and streamlines resource usage” said Prof. Carolina Wählby, Principle Investigator for the HASTE project. Read the full article.
The HASTE team are pleased to announce the availability of a new publication of the arXiv pre-print service: ‘Apache Spark Streaming and HarmonicIO: A Performance and Architecture Comparison‘. We performed a benchmark analysis to compare two stream processing frameworks – the popular, Apache Spark framework, widely used in industry, and our own framework HarmonicIO (presented this summer at IEEE Cloud 2018 in San Francisco ).
Previous studies have demonstrated that Apache Spark, Flink and related frameworks can perform stream processing at very high frequencies, but they tend to focus on small messages with a computationally light ‘map’ stage for each message; a common enterprise use case (for example, processing JSON documents). In academic HPC contexts, we often want to analyze larger messages, with more CPU-intensive computations. Our study adds to these benchmarks by broadening the domain to include such processing loads – larger messages (leading to network-bound throughput), and that are computationally intensive (leading to CPU-bound throughput) in the map phase; in order to evaluate applicability of these frameworks to scientific computing applications.
We find that relative performance varies considerably across this domain, with the chosen means of stream source integration having a big impact. Most interestingly, we find that Spark performs very well for large (~10Mb) and small message sizes (~1Kb), but for medium-sized messages, it can be out-performed by HarmonicIO in some configurations. These message sizes are relevant to HASTE, because such file sizes are typical of microscopy applications.
We offer recommendations for choosing and configuring the frameworks, and present a benchmarking toolset developed for this study.
We had a successful project meeting in Uppsala/Stockholm last month – Håkan Wieslander presented his latest research on image feature analysis, Phil Harrison his latest conformal prediction models, Ben Blamey demonstrated the prototype HASTE pipeline, Niharika Gauraha her work on SVM+. Alan Sabirsh and Johan Karlsson explained a little more about their work at Astrazeneca.
On day 2, we visited Vironova in Stockholm, and were treated to a hands-on demo of their MiniTEM electron microscope – and discussed plans for the next project phase.
Oliver’s MSc thesis will investigate intelligent ways to manage and position docker containers in a VM environment, in order to improve efficiency in physical resource usage and maintain performance. The implementation of such a controller system will be developed in coordination with the HarmonicIO streaming framework used in HASTE, which will help the automatic scaling of containers working in the system as well as evaluate the design with a real use case.
Discovering new drugs is becoming more costly. Lars Carlsson gave a presentation Machine Learning For Smarter Drug Discovery at RISE SICS Data Science & AI Day, Nov 28, 2017, where he gave some examples of how AstraZeneca is trying to improve the drug discovery phases through the use of machine learning.
We welcome Phil Harrison as new PhD Student in the Spjuth lab. Phil obtained his first PhD in marine biology in 2006 studying the population dynamics of grey seals. Between 2006-2016 he undertook several research projects modelling wildlife populations and analysing trends in biodiversity. In the HASTE project, Phil will develop machine learning methods for online, large-scale analysis of microscopy image data based on statistical earning including e.g. conformal prediction and probabilistic prediction.